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Efficient Syntheses of 2-(3',5'-Difluorophenyl)-3-(4'-methylsulfonylphenyl)-cyclopent-2-enone, a Potent COX-2 Inhibitor

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Keywords: Acylation; Alkylation; COX-II inhibitor; Suzuki coupling; Synthesis

Document Type: Research Article

DOI: http://dx.doi.org/10.1016/S0040-4020(99)00274-4

Affiliations: Medicinal Chemistry Department, Merck Frosst, Quebec, H9H 3L1, Canada

Publication date: May 7, 1999

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