Publisher: Elsevier

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Volume 74, Number 2, March 2000

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Cholinergic receptors and neurodegenerative diseases
pp. 85-89(5)
Author: Gualtieri, F.

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Central nicotinic receptor ligands and pharmacophores
pp. 103-114(12)
Authors: Glennon, R.A.; Dukat, M.

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Structural aspects of high affinity ligands for the α42 neuronal nicotinic receptor
pp. 115-123(9)
Authors: Dart, M.J.; Wasicak, J.T.; Ryther, K.B.; Schrimpf, M.R.; Kim, K.H.; Anderson, D.J.; Sullivan, J.P.; Meyer, M.D.

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Recombinant human receptors and functional assays in the discovery of altinicline (SIB-1508Y), a novel acetylcholine-gated ion channel (nAChR) agonist
pp. 125-130(6)
Authors: Cosford, N.D.P.; Bleicher, L.; Vernier, J.; Chavez-Noriega, L.; Rao, T.S.; Siegel, R.S.; Suto, C.; Washburn, M.; Lloyd, G.K.; McDonald, I.A.

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Design and development of selective muscarinic agonists for the treatment of Alzheimer's disease: characterization of tetrahydropyrimidine derivatives and development of new approaches for improved affinity and selectivity for M1 receptors
pp. 135-140(6)
Authors: Messer, W.S.; Rajeswaran, W.G.; Cao, Y.; Zhang, H.; El-Assadi, A.A.; Dockery, C.; Liske, J.; O'Brien, J.; Williams, F.E.; Huang, X.; Wroblewski, M.E.; Nagy, P.I.; Peseckis, S.M.

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CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology
pp. 141-148(8)
Authors: Tecle, H.; Schwarz, R.D.; Barrett, S.D.; Callahan, M.J.; Caprathe, B.W.; Davis, R.E.; Doyle, P.; Emmerling, M.; Lauffer, D.J.; Mirzadegan, T.; Moreland, D.W.; Lipiniski, W.; Nelson, C.; Raby, C.; Spencer, C.; Spiegel, K.; Thomas, A.J.; Jaen, J.C.

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Ligands for the common allosteric site of acetylcholine M2-receptors: development and application
pp. 149-155(7)
Authors: Holzgrabe, U.; Bender, W.; Botero Cid, H.M.; Staudt, M.; Pick, R.; Pfletschinger, C.; Balatkova, E.; Trankle, C.; Mohr, K.

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Receptors in cardiovascular disease: review and introduction
pp. 157-161(5)
Authors: Leonardi, A.; Sironi, G.; Motta, G.

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The α1a and α1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action
pp. 173-179(7)
Authors: Cotecchia, S.; Rossier, O.; Fanelli, F.; Leonardi, A.; de Benedetti, P.G.

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α1-Adrenoreceptor antagonists bearing a quinazoline or a benzodioxane moiety
pp. 181-190(10)
Authors: Melchiorre, C.; Angeli, P.; Bolognesi, M.L.; Chiarini, A.; Giardina, D.; Gulini, U.; Leonardi, A.; Marucci, G.; Minarini, A.; Pigini, M.; Quaglia, W.; Rosini, M.; Tumiatti, V.

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Selection, design and evaluation of new radioligands for PET studies of cardiac adrenoceptors
pp. 191-200(10)
Authors: Pike, V.W.; Law, M.P.; Osman, S.; Davenport, R.J.; Rimoldi, O.; Giardina, D.; Camici, P.G.

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Enigmatic receptors
pp. 201-203(3)
Author: Brasili, L.

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Imidazoline receptors: a challenge
pp. 205-209(5)
Authors: Bousquet, P.; Bruban, V.; Schann, S.; Feldman, J.

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Excitatory amino acid receptors
pp. 219-220(2)
Author: Gaviraghi, G.

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Metabotropic glutamate receptors: a structural view point
pp. 231-237(7)
Authors: Pellicciari, R.; Costantino, G.; Macchiarulo, A.

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Synthesis and pharmacological properties of novel glycine antagonists
pp. 239-245(7)
Authors: Donati, D.; Di Fabio, R.

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Receptors in neurodegenerative diseases
pp. 247-251(5)
Author: Froestl, W.

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Neurotrophin receptor structure and interactions
pp. 253-260(8)
Authors: Yano, H.; Chao, M.V.

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The ciliary neurotrophic factor and its receptor, CNTFRα
pp. 265-272(8)
Authors: Sleeman, M.W.; Anderson, K.D.; Lambert, P.D.; Yancopoulos, G.D.; Wiegand, S.J.

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Apoptosis induced by death receptors
pp. 281-286(6)
Authors: Schneider, P.; Tschopp, J.

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Hijacked receptors
pp. 287-290(4)
Author: Triggle, D.J.

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ICAM-1 receptors and cold viruses
pp. 291-297(7)
Authors: Bella, J.; Rossmann, M.G.

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Viral-encoded G-protein coupled receptors: new targets for drug research?
pp. 299-304(6)
Authors: Smit, M.J.; Timmerman, H.; Verzijl, D.; Leurs, R.

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Chemokine receptors: interaction with HIV-1 and viral-encoded chemokines
pp. 305-312(8)
Authors: Sozzani, S.; Allavena, P.; Vecchi, A.; van Damme, J.; Mantovani, A.

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General topics and perspectives
pp. 313-314(2)
Author: Timmerman, H.

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Pharmacological evidence of muscarinic receptor heterodimerization
pp. 315-326(12)
Authors: Chiacchio, S.; Scarselli, M.; Armogida, M.; Maggio, R.

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Constitutive activity of G protein coupled receptors and drug action
pp. 327-331(5)
Authors: Leurs, R.; Pena, M.S.R.; Bakker, R.A.; Alewijnse, A.E.; Timmerman, H.

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New dimensions in G protein signalling: G5 and the RGS proteins
pp. 333-336(4)
Authors: Simonds, W.F.; Zhang, J.

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Kappa opioid agonists as targets for pharmacotherapies in cocaine abuse
pp. 337-344(8)
Authors: Neumeyer, J.L.; Mello, N.K.; Stevens Negus, S.; Bidlack, J.M.

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