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Species comparison in P450 induction: effects of dexamethasone, omeprazole, and rifampin on P450 isoforms 1A and 3A in primary cultured hepatocytes from man, Sprague-Dawley rat, minipig, and beagle dog

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Keywords: Cytochromes P450; Dog hepatocytes; Drug-drug interactions; Enzyme induction; Human hepatocytes; In vitro metabolism; Minipig hepatocytes; Monkey hepatocytes; Rat hepatocytes; Species differences

Document Type: Research Article

DOI: http://dx.doi.org/10.1016/S0009-2797(01)00162-4

Affiliations: In Vitro Technologies Inc., 1450 South Rolling Road, 20227, Baltimore, MD, USA

Publication date: May 16, 2001

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