Mechanism-based inhibition of rat liver microsomal diazepam C₃-hydroxylase by mifepristone associated with loss of spectrally detectable cytochrome P450

Authors: Reilly P.E.B.; Gomi R.J.; Mason S.R.

Source: Chemico-Biological Interactions, Volume 118, Number 1, 1 March 1999 , pp. 39-49(11)

Publisher: Elsevier

Keywords: CYP3A; Cytochrome P450; Heme thiolate protein; Food deprivation; Diazepam C₃-hydroxylase; Mifepristone; RU486; Monooxygenase induction; Mechanism-based inhibition; Dexamethasone

Language: English

Document Type: Research article

DOI: http://dx.doi.org/10.1016/S0009-2797(98)00115-X

Publication date: 1999-03-01

• In this: publication
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• In this Subject: Anatomy & Physiology ,  Biology ,  Ecology ,  Toxicology ,  Biochemistry
• By this author: Reilly P.E.B. ;  Gomi R.J. ;  Mason S.R.

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