In vitro pharmacokinetics and pharmacodynamics of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)

Authors: Ueda-Kawamitsu H.; Lawson T.A.; Gwilt P.R.

Source: Biochemical Pharmacology, Volume 63, Number 7, 1 April 2002 , pp. 1209-1218(10)

Publisher: Elsevier

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Keywords: BCNU; Pharmacokinetics; Pharmacodynamics; DNA interstrand cross-links; Cell cycle; Cell death

Language: English

Document Type: Research article

DOI: http://dx.doi.org/10.1016/S0006-2952(02)00878-X

Affiliations: 1: Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, 600 South 42nd Street, P.O. Box 986025, 68198-6025, Omaha, NE, USA

Publication date: 2002-04-01

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