Inhibition of Microsomal Cytochromes P450 in Rat Liver by the TricycleC Antidepressant Drug Desipramine and Its Primary Oxidized Metabolites

Authors: McNeil C.M.; Murray M.1

Source: Biochemical Pharmacology, Volume 51, Number 1, 12 January 1996 , pp. 15-20(6)

Publisher: Elsevier

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Keywords: tricyclic antidepressants; cytochrome P450; metabolite-intermediate complexation; pharmacokinetic interactions

Language: English

Document Type: Research article

DOI: 10.1016/0006-2952(95)02105-1

Affiliations: 1: Storr Liver Unit, Department of Medicine, University of Sydney, Westmead Hospital, Westmead, NSW 2145, Australia

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