Various strategies are being developed for the prevention of implant-related infections. One of them is the encapsulation of antimicrobial drugs in inorganic containers that can be released at the site of the implant. However, the attachment of such containers onto implant surfaces may be a challenge. In this study, it is demonstrated that CeO&60;sub&62;2&60;/sub&62; nanocontainers can be added to a TiO&60;sub&62;2 &60;/sub&62;coating on glass surfaces. The structure, crystal phase and surface properties of the nanocontainers were characterized by transmission electron microscopy, scanning electron microscopy (SEM), powder X-ray diffraction, infrared spectroscopy, Raman spectroscopy and a zetasizer. The coatings were analyzed by SEM and energy-dispersive X-ray spectroscopy to determine their homogeneity and ensure CeO&60;sub&62;2&60;/sub&62; encapsulation. The coatings were stable in air over prolonged time periods (>&59; 6 months) and therefore hold promise for pursuing in biomedical applications.
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Document Type: Research Article
PFPC, School of Chemistry, The University of Melbourne, Melbourne, Victoria 3010, Australia
Department of Chemistry and Fribourg Center for Nanomaterials, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland
Publication date: 01 January 2016