Cancer Stem Cell Research: Current Situation and Problems
Authors: Kobayashi, Naoya; Navarro-Alvarez, Nalú; Soto-Gutierrez, Alejandro; Kawamoto, Hironobu; Kondo, Yoshitaka; Yamatsuji, Tomoki; Shirakawa, Yasuhiro; Naomoto, Yoshio; Tanaka, Noriaki
Source: Cell Transplantation, Volume 17, Numbers 1-2, 2008 , pp. 19-25(7)
Publisher: Cognizant Communication Corporation
Abstract:The concept of a “cancer stem cell system” that continues to supply cancer component cells has been proposed. It is time to apply stem cell studies, which is a field of expertise in regenerative medicine, to cancer treatment. Cancer treatments that effectively attack cancer stem cells acting as a manufacturing plant for producing differentiated cancer progenies will be designed by revealing the cancer stem cell system. Therefore, in the near future we hope that revolution will occur in cancer therapy to eradicate cancer and prevent the recurrence thereof. In this review we discuss the current situation and problems of cancer stem cell research.
Document Type: Research Article
Affiliations: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Publication date: 2008-01-01
- Cell Transplantation publishes original, peer-reviewed research and review articles on the subject of cell transplantation and its application to human diseases. To ensure high-quality contributions from all areas of transplantation, separate section editors and editorial boards have been established. Articles deal with a wide range of topics including physiological, medical, preclinical, tissue engineering, and device-oriented aspects of transplantation of nervous system, endocrine, growth factor-secreting, bone marrow, epithelial, endothelial, and genetically engineered cells, among others. Basic clinical studies and immunological research papers are also featured. To provide complete coverage of this revolutionary field, Cell Transplantation will report on relevant technological advances, and ethical and regulatory considerations of cell transplants. Cell Transplantation is now an Open Access journal starting with volume 18 in 2009, and therefore there will be an inexpensive publication charge, which is dependent on the number of pages, in addition to the charge for color figures. This will allow work to be disseminated to a wider audience and also entitle the corresponding author to a free PDF, as well as prepublication of an unedited version of the manuscript.
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- In this Subject: Anatomy & Physiology , Biology , Biotechnology , Pharmacology , Surgery
- By this author: Kobayashi, Naoya ; Navarro-Alvarez, Nalú ; Soto-Gutierrez, Alejandro ; Kawamoto, Hironobu ; Kondo, Yoshitaka ; Yamatsuji, Tomoki ; Shirakawa, Yasuhiro ; Naomoto, Yoshio ; Tanaka, Noriaki