According to the National Institute of Allergy and Infectious Disease (NIAID), scientific research and development provide America with the most appropriate outcomes for the advancement of medical tools necessary to effectively respond to a future biological attack (5,6). The NIAID suggests that the nation's ability to detect and counter a bioterrorist attack requires basic research aimed at understanding pathogens that have the potential to be used as agents of bioterrorism and how human immune systems respond to those pathogens (5,6). Most important for this editorial, it is anticipated that this basic research will be applied to the development of new and improved diagnostic tests, vaccines, and therapies (5,6). Integral to this research are the disciplines that comprise the medical sciences closely associated with cell transplantation. The basic sciences of medical microbiology and immunology, biochemistry and molecular biology, human anatomy and physiology, pharmacology and therapeutics, pathology, neuroscience, and many of the clinical fields of organ and cell transplantation provide the core disciplines to advance biodefense and homeland security research. Clearly, the fields of biology, public health, the physical sciences, and engineering also will play a critical role in furthering this research agenda (4–6). Some of the largest budget increases of the NIH and in the Department of Homeland Security will be in biological defense (1–3). This provides an opportunity to advance the fields of cell therapy and transplantation by leveraging research areas being sponsored in the new federal initiative. Specific areas of research include (5,6):
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Publication date: January 1, 2003
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Cell Transplantation publishes original, peer-reviewed research and review articles on the subject of cell transplantation and its application to human diseases. To ensure high-quality contributions from all areas of transplantation, separate section editors and editorial boards have been established. Articles deal with a wide range of topics including physiological, medical, preclinical, tissue engineering, and device-oriented aspects of transplantation of nervous system, endocrine, growth factor-secreting, bone marrow, epithelial, endothelial, and genetically engineered cells, among others. Basic clinical studies and immunological research papers are also featured. To provide complete coverage of this revolutionary field, Cell Transplantation will report on relevant technological advances, and ethical and regulatory considerations of cell transplants. Cell Transplantation is now an Open Access journal starting with volume 18 in 2009, and therefore there will be an inexpensive publication charge, which is dependent on the number of pages, in addition to the charge for color figures. This will allow work to be disseminated to a wider audience and also entitle the corresponding author to a free PDF, as well as prepublication of an unedited version of the manuscript.