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BOOK REVIEW: Stem Cells and CNS Development Mahendra Rao, Editor (Humana Press, 2001, ISBN 0-89603-886-6)

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In the last two decades, the field of stem cell neurobiology has become one of the hottest, most rapid growing arenas in neuroscience. When, as a very young scientist, I entered the field of progenitor biology under the guidance of Professor Pasquale Graziadei at Florida State University, thoughts about neuronal turnover and migration of cells were not often the subjects of discussion. The existence of “dreaming pools” of immature cells that could serve as replacements for existing neuronal populations within the brains of either birds or rodents became obvious much later. But beginning in the early 1990s, knowledge in this field grew like an avalanche. Today, no one doubts the existence of stem/progenitor cells within the brain, and scientists, like enthusiastic prospectors, have turned their attention to the next level, exploring the properties of these valuable cell sources and developing methods to utilize them in various therapeutic treatments. The development of therapeutic treatments, however, requires extensive and thorough knowledge of the properties and characteristics of these cells within their natural brain environment. This book, Stem Cells and CNS Development, edited by Mahendra Rao, has appeared exactly at the right time to provide this essential information.

Document Type: Book Review


Affiliations: Center on Aging and Brain Repair, Depts. of Neurosurgery, Anatomy and Pharmacology, University of South Florida, College of Medicine, Tampa, FL 33612

Publication date: 2002-01-01

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  • Cell Transplantation publishes original, peer-reviewed research and review articles on the subject of cell transplantation and its application to human diseases. To ensure high-quality contributions from all areas of transplantation, separate section editors and editorial boards have been established. Articles deal with a wide range of topics including physiological, medical, preclinical, tissue engineering, and device-oriented aspects of transplantation of nervous system, endocrine, growth factor-secreting, bone marrow, epithelial, endothelial, and genetically engineered cells, among others. Basic clinical studies and immunological research papers are also featured. To provide complete coverage of this revolutionary field, Cell Transplantation will report on relevant technological advances, and ethical and regulatory considerations of cell transplants. Cell Transplantation is now an Open Access journal starting with volume 18 in 2009, and therefore there will be an inexpensive publication charge, which is dependent on the number of pages, in addition to the charge for color figures. This will allow work to be disseminated to a wider audience and also entitle the corresponding author to a free PDF, as well as prepublication of an unedited version of the manuscript.
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