There have been great advances made in the field of transplantation, and a wide variety of organs are clinically available. However, there exist serious problems such as shortage of donor organs and lifelong immunosuppression. These shortcomings have stimulated investigation into cell therapy instead of entire organ transplantation because the approach has many potential advantages. If functional tissue could be reconstructed using cell therapy, this would overcome the problem of the donor organ shortages by using cells from a small amount of donor tissue and expanding them in vitro to create a potentially limitless supply. Cell therapy will be evaluated as one of the most important and innovative therapy in the medical field in the very near future of the 21st century.
Department of Organ Reconstruction, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, Kyoto 606-8507, Japan
Publication date: January 1, 2001
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Cell Transplantation publishes original, peer-reviewed research and review articles on the subject of cell transplantation and its application to human diseases. To ensure high-quality contributions from all areas of transplantation, separate section editors and editorial boards have been established. Articles deal with a wide range of topics including physiological, medical, preclinical, tissue engineering, and device-oriented aspects of transplantation of nervous system, endocrine, growth factor-secreting, bone marrow, epithelial, endothelial, and genetically engineered cells, among others. Basic clinical studies and immunological research papers are also featured. To provide complete coverage of this revolutionary field, Cell Transplantation will report on relevant technological advances, and ethical and regulatory considerations of cell transplants. Cell Transplantation is now an Open Access journal starting with volume 18 in 2009, and therefore there will be an inexpensive publication charge, which is dependent on the number of pages, in addition to the charge for color figures. This will allow work to be disseminated to a wider audience and also entitle the corresponding author to a free PDF, as well as prepublication of an unedited version of the manuscript.