Accurate determination of quadruplex binding affinity and potency of G-quadruplex-interactive telomerase inhibitors by use of a telomerase extension assay requires varying the primer concentration

Authors: Cathers B.1; Sun D.2; Hurley L.1

Source: Anti-Cancer Drug Design, Volume 14, Number 4, 1999 , pp. 367-372(6)

Publisher: Cognizant Communication Corporation

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Keywords: anthraquinone; assay; G-qudruplex; inhibition; telomerase

Document Type: Research article

Affiliations: 1: DSun LHHey Drug Dynamics Institute, College of Pharmacy, The University of Texas at Austin, Austin, TX 78712-1074, USA 2: Institute for Drug Development, 14960 Omicron Drive, San Antonio, TX 78245-3217, USA

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