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Open Access Fabrication of Silicon Carbide Quantum Dots (QDs) for Labeling Living Cell via Chemical Etching Method and Its Optical Properties

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Silicon carbide nanoparticles fabricated via self-propagating high-temperature synthesis (SHS) were etched in the mixture solution of nitric and hydrofluoric acid. The non-cytotoxic labeling material of silicon carbide quantum dots (QDs) were prepared by ultrasonic cavitation and high-speed centrifugation. The microstructure and optical performance of SiC QDs were analyzed. The living cell of Aureobasidium pulluans was labeled and observed by long-term-distance fluorescence imaging analysis. The results show that the SiC particles prepared by SHS are formed as a grid-like hollow structure in the mixture acid solution. The SiC QDs in the size range from 1 to 2.5 nm were fabricated by cavitation crushing with ultrasound and chromatography with high-speed centrifugal force, leading to the size of less than the corresponding exciton Bohr diameter (5.4 nm) for the intensive photoluminescence. Moreover, the SiC QDs prepared have a superior biocompatibility. In addition, the mechanism on the labeling and long-term-distance fluorescence imaging analysis of the living cells was also discussed.

Keywords: Aureobasidium pulluanssilicon; chemical etching; labeling living cells; photoluminescence; silicon carbide quantum dots

Document Type: Research Article


Affiliations: 1: Mechanical and Electronic Engineering College, Shandong Agricultural University, Tai’an 271018, Shandong, China 2: Shandong Provincial Key Laboratory of Horticultural Machineries and Equipments Shandong Agricultural University, Tai’an 271018, China 3: Department of Materials Science and Engineering, Pohang University of Science and Technology, Pohang 790784, Korea

Publication date: December 1, 2013

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  • Journal of the Chinese Ceramic Society (JCCS), published in Chinese and in English, is a comprehensive monthly periodical focused on the fields of inorganic and non-metallic materials. The main purpose of the JCCS is to report the latest creative achievements in research, production and design for ceramics, glass, cementing materials, refractory, artificial crystals and other non-metallic materials. JCCS is regarded as an important journal in inorganic and non-metallic materials sciences in China and has been awarded by China Association for Science and Technology. The full-text of papers in JCCS is also published by CNKI (China National Knowledge Infrastructure). JCCS is indexed in EI Compendex, CA( Chemical Abstracts) ,SA and Ж and more than 20 databases.
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