@article {Koerner:June 1998:0042-9007:213, author = "Koerner, K.", author = "Cardoso, M.", author = "Dengler, Th.", author = "Kerowgan, M.", author = "Kubanek, B.", title = "Estimated Risk of Transmission of Hepatitis C Virus by Blood Transfusion", journal = "Vox Sanguinis", volume = "74", year = "June 1998", abstract = "
Objective: The risk of transmitting hepatitis C (HCV) by transfusion of anti-HCV-negative screened blood was estimated for the blood donor population of Baden-Württemberg (southwestern Germany). Methods: The data from the blood donors screened for anti-HCV and for HBsAg during 1990-1995 were analyzed. Results: The prevalence of confirmed anti-HCV-positive blood donations decreased continuously during the last 5 years, reaching 121 per 100,000 blood donations. A higher anti-HCV prevalence rate was found in female than in male blood donors (p<0.05). The estimated risk of transmitting HCV during the window period is 1:200,000 (1:97,000-1:1,400,000) for repeat donors. In 1995, the calculated risk for first-time donors was 1:20,000 (1:15,000-28,000). The incidence for HCV was 1.2 per 100,000 blood donations. Conclusion: The risk of transmitting hepatitis C by blood transfusion is low. Additional tests to shorten the window period to detect antibodies to HCV might increase the safety of blood transfusion.", pages = "213-216(4)", url = "http://www.ingentaconnect.com/content/bsc/vox/1998/00000074/00000004/art00001" doi = "doi:10.1046/j.1423-0410.1998.7440213.x" }