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De Novo Membranoproliferative Glomerulonephritis III in a renal transplant patient: Case report and review of the literature

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Idiopathic membranoproliferative glomerulonephritis (MPGN) is a rare cause of renal failure with a cumulative incidence of 0.3% of all ESRD and 4% of all primary glomerulonephritis for types I and II. Membranoproliferative glomerulonephritis type III is more uncommon and idiopathic de novo MPGN III in a renal transplant patient has not been reported. We present the case of a 57‐year old white female patient with a diagnosis of lithium toxicity as cause of end stage renal disease (ESRD) who developed MPGN III in her allograft 6 years after a renal transplant. Despite treatment, she progressed to ESRD within four and a half years from the time of diagnosis.
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Document Type: Research Article

Affiliations: 1:  Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA 2:  Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO,USA

Publication date: 2012-05-01

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