Skip to main content

Free Content Plasma vitamin C assay in women of reproductive age in Kampala, Uganda, using a colorimetric method

Download Article:

You have access to the full text article on a website external to Ingenta Connect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library


Objective  Vitamin C alone or in combination with vitamin E has been proposed to prevent pre‐eclampsia. In this study, we assayed the plasma vitamin C in women of reproductive age in Kampala and assessed its association with pre‐eclampsia.

Methods  Participants in this study were 215 women with pre‐eclampsia, 400 women with normal pregnancy attending antenatal clinic and 200 non‐pregnant women attending family planning clinic at Mulago Hospital’s Department of Obstetrics and Gynaecology from 1st May 2008 to 1st May 2009. Plasma vitamin C was assayed using the acid phosphotungstate method; differences in the means of plasma vitamin C were determined by anova.

Results  Mean plasma vitamin C levels were 1.72 (SD 0.68) × 103 μg/l in women with pre‐eclampsia, 1.89 (SD 0.73) × 103 μg/l in women with normal pregnancy and 2.64 (SD 0.97) × 103 μg/l in non‐pregnant women. Plasma vitamin C was lower in women with pre‐eclampsia than in women with normal pregnancy (P = 0.005) and non‐pregnant women (P < 0.001).

Conclusion  Health workers need to advise women of reproductive age on foods that are rich in vitamin C, as this may improve the vitamin status and possibly reduce the occurrence of pre‐eclampsia.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Language: English

Document Type: Research Article

Affiliations: 1:  Department of Obstetrics and Gynaecology, Makerere University College of Health Sciences, Kampala, Uganda 2:  School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda 3:  Department of Obstetrics and Gynaecology, Walter Sisulu University, Mthatha, South Africa 4:  Department of Pathology, Makerere University College of Health Sciences, Kampala, Uganda 5:  Department of Health, Uganda Christian University, Mukono, Uganda

Publication date: 2012-02-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more