Skip to main content

Free Content Clinical predictors and outcome of hypoxaemia among under‐five diarrhoeal children with or without pneumonia in an urban hospital, Dhaka, Bangladesh

Download Article:

You have access to the full text article on a website external to Ingenta Connect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library

Abstract

Objective  To explore the predictors and outcome of hypoxaemia in children under 5 years of age who were hospitalized for the management of diarrhoea in Dhaka, where comorbidities are common.

Methods  In a prospective cohort study, we enrolled all children <5 years of age admitted to the special care ward (SCW) of the Dhaka Hospital of ICDDR,B from September to December 2007. Those who presented with hypoxaemia (SpO2 < 90%) constituted the study group, and those without hypoxaemia formed the comparison group.

Results  A total of 258 children were enrolled, all had diarrhoea. Of the total, 198 (77%) had pneumonia and 106 (41%) had severe malnutrition (<−3 Z‐score of weight for age of the median of the National Centre for Health Statistics), 119 (46%) had hypoxaemia and 138 children did not have hypoxaemia at the time of admission. Children with hypoxaemia had a higher probability of a fatal outcome (21%vs. 4%; P < 0.001). Using logistic regression analysis, the independent predictors of hypoxaemia at the time of presentation were lower chest wall indrawing [OR 6.91, 95% confidence intervals (CI) 3.66–13.08, P < 0.001], nasal flaring (OR 3.22, 95% CI 1.45–7.17, P = 0.004) and severe sepsis (OR 4.48, 95% CI 1.62–12.42, P = 0.004).

Conclusion  In this seriously ill population of children with diarrhoea and comorbidities, hypoxaemia was associated with high case–fatality rates. Independent clinical predictors of hypoxaemia in this population, identifiable at the time of admission, were lower chest wall indrawing, nasal flaring and the clinical syndrome of severe sepsis.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Language: English

Document Type: Research Article

Affiliations:  Clinical Sciences Division, ICDDR,B, Dhaka, Bangladesh

Publication date: 2012-01-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more