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Free Content High proportion of mixed-species Plasmodium infections in India revealed by PCR diagnostic assay

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Summary Accurate diagnosis is the key to effective treatment and control of malaria. We screened 180 microscopically diagnosed Indian malaria-positive blood samples for pure and mixed infections by and . An unusually high proportion of mixed infections was detected, signifying the sensitivity of PCR assay over traditional microscopic diagnosis.

Le diagnostic précis est la clé pour un traitement efficace et pour la lutte contre la malaria. Nous avons examiné 180 échantillons de sang provenant de l’Inde, diagnostiqués microscopiquement comme positifs pour la malaria, afin de détecter des infections uniques et mixtes àPlasmodium falciparum et P.vivax. Une proportion exceptionnellement élevée d’infections mixtes a été détectée, ce qui confirme la sensibilité plus élevée de la PCR par rapport au diagnostic microscopique traditionnel.

Keywords: Inde; India; PCR; PCR assay; diagnostic de la malaria; diagnóstico de malaria; infecciones mixtas; infections mixtes; malaria diagnosis; microscopie; microscopy; microscopía; mixed infections

Document Type: Research Article


Affiliations: 1:  National Institute of Malaria Research, Dwarka, New Delhi, India 2:  World Health Organization-South East Asian Regional Office, New Delhi, India

Publication date: 2010-07-01

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