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Free Content Default during TB diagnosis: quantifying the problem

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Summary Objectives  To quantify default during diagnosis in TB suspects and in smear-positive cases; to investigate sex differences in default during diagnosis, in all of Pakistan. Methods  Data from laboratory registers were collected on 12 216 suspects in nine districts over the period July–September 2008. Results  A total of 1573 TB suspects (12.9%, 95% CI = 12.3–13.5) dropped out of the diagnostic process after initial sputum submission. A total of 2058 smear-positive cases were detected, and of these 107 (5.2%, 95% CI = 4.2–6.2) defaulted during diagnosis and therefore could not be started on treatment. Male suspects defaulted slightly more frequently than female suspects (=0.0268). Conclusion  Default during diagnosis is a frequent occurrence in Pakistan that should be monitored and addressed by TB control programs.

French
Désistement lors du diagnostic de la tuberculose: quantifier le problème Objectifs: 

Quantifier le désistement lors du diagnostic chez les cas suspects de tuberculose (TB) et chez les cas à frottis positif, investiguer les différences entre sexes dans le désistement lors du diagnostic dans tous le Pakistan. Méthode: 

Les données sur 12216 suspects ont été collectées des registres de laboratoire dans 9 districts durant la période de juillet à septembre 2008. Résultats: 

1573 suspects TB (12,9%; IC95%: 12,3 – 13,5) ont abandonné le processus de diagnostic après la première soumission de crachat. 2058 cas à frottis positif ont été détectés dont 107 (5,2%, IC95%: 4,2 - 6,2) ont désisté lors du diagnostic, ne pouvant dès lors pas être mis sous traitement. Les suspects masculins désistaient un peu plus fréquemment que les suspects féminins (p = 0,0268). Conclusion: 

Le désistement lors du diagnostic est un phénomène fréquent au Pakistan qui devrait être suivi et adressé par les programmes de lutte antituberculeuse.
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Keywords: Tuberculosis; búsqueda de casos; case finding; cuantitativo; diagnosis; diagnostic; diagnóstico; dépistage des cas; quantitative; tuberculose; tuberculosis

Document Type: Short Communication

Affiliations: 1:  London School of Hygiene and Tropical Medicine, London, UK 2:  Aga Khan University Hospital, Karachi, Pakistan

Publication date: 2009-12-01

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