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Free Content Monitoring for multidrug‐resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola

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Abstract:

Objectives  To assess the extent of drug resistance in Uige through molecular genetic analysis and to test whether the dhfr triple mutant alleles present in Angola are of southeast Asian origin.

Keywords: Angola; Plasmodium falciparum; drug resistance molecular markers; evolución resistencia pirimetamina; marcadores molecular de resistencia a fármacos; microsatellites; microsatélites; pyrimethamine resistance evolution

Language: English

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1365-3156.2009.02369.x

Affiliations: 1:  Department of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy 2:  Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK 3:  CUAMM-Angola, Luanda, Angola 4:  Angotrip Project, Caritas, Luanda, Angola 5:  Provincial Hospital, Uige, Angola 6:  Centre for Tropical Diseases, S. Cuore Hospital, Negrar, Italy

Publication date: 2009-10-01

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