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Free Content Elimination of lymphatic filariasis in the Republic of Korea: an epidemiological survey of formerly endemic areas, 2002–2006

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Abstract:

Summary Objectives  To determine the current status of lymphatic filariasis (LF) in Korea. Methods  Epidemiological surveys between 2002 and 2006 in areas where LF was previously endemic: remote and coastal areas Jeollanam-do, Gyeongsangnam-do, and Jeju-do, and inland Gyeongsangbuk-do. We took night blood smears from 9426 people for microfilaria testing and assayed samples from 3049 children (10- to 13-year-olds) and 1526 adults for antibodies. Results  We found two cases (0.01%) with low microfilaria density in their peripheral blood (1–2/20 μl) on the remote island of Jeollanam-do in the southern part of the Korean peninsula. These patients, males over 60-years old, were treated with diethylcarbamazine (DEC). None of the 4575 people surveyed tested positive for specific antibodies. Conclusion  Lymphatic filariasis appears to have been eliminated in Korea.

French
Objectifs: 

Déterminer l’état actuel de la filariose lymphatique (FL) en Corée. Méthodes: 

Enquêtes épidémiologiques menées entre 2002 et 2006 dans les zones où la FL étaient endémique: régions côtières de Jeollanam-do et de Gyeongsangnam-do, Jeju-do et région de l’intérieur Gyeongsangbuk-do. Nous avons effectué des frottis sanguins nocturnes chez 9426 personnes, testés pour les microfilaires et avons testé les échantillons de 3049 enfants de 10-13 ans et de 1526 adultes pour les anticorps de Brugia malayi. Résultats: 

Nous avons trouvé 2 cas (0,01%) avec une faible densité de microfilaires dans leur sang périphérique (1-2/20ul) sur l’île lointaine de Jeollanam-do dans la partie sud de la péninsule coréenne. Ces patients masculins de plus de 60 ans ont été traités avec la diéthylcarbamazine (DEC). Aucun des 4575 personnes surveillées n’a testé positif pour les anticorps anti B. malayi. Conclusion: 

La filariose lymphatique semble avoir étééliminée en Corée.

Keywords: B. malayi; eliminación; elimination; enquête épidémiologique; epidemiological survey; estudio epidemiológico; filariasis linfática; filariose lymphatique; lymphatic filariasis; microfilaires; microfilaria; élimination

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1365-3156.2009.02240.x

Affiliations: 1:  Division of Malaria & Parasitic Diseases, National Institute of Health, Seoul, Korea 2:  Department of Molecular Parasitology and Samsung Research Institute, Sungkyunkwan University School of Medicine, Suweon, Korea

Publication date: 2009-04-01

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