Skip to main content

Free Content Short communication: Trypanosoma cruzi lineage I in endomyocardial biopsy from a north-eastern Brazilian patient at end-stage chronic chagasic cardiomyopathy

Download Article:

You have access to the full text article on a website external to ingentaconnect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library

Abstract:

Summary

Trypanosoma cruzi, the agent of Chagas disease, is genetically classified into two major evolutionary lineages, T. cruzi I and T. cruzi II. In Southern American Cone countries it is T cruzi II which causes most cases of severe chronic Chagas disease. Contrary to this, we isolated T. cruzi I nested in endomyocardial biopsies of a chronic chagasic patient with end-stage heart failure. Our finding should alert clinicians to the possibility of severe Chagas disease in all regions where T. cruzi circulates, regardless of its lineage.

Keywords: Chagas disease; T. cruzi lineages; Trypanosoma cruzi; cardiomyopathy; endomyocardial biopsy; genetic typing

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1365-3156.2006.01575.x

Affiliations: 1: Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil 2: Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, SP, Brazil 3: Laboratório de Imunologia, Instituto do Coração, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil 4: Divisão de Cirurgia, Instituto do Coração, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil

Publication date: March 1, 2006

bsc/tmih/2006/00000011/00000003/art00006
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more