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Free Content Isolation of a Plasmodium vivax refractory Anopheles culicifacies strain from India

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Anopheles culicifaciessensu lato comprises five sibling species. We report the isolation of an An. culicifacies species B strain which is completely refractory to Plasmodium vivax sporogonic development and partially refractory to P. falciparum. Parasite development in this strain is arrested by a melanotic encapsulation mechanism in the mid-gut. We compare the infectivity of this refractory strain and four other species B strains from different epidemiological zones of India with P. vivax in the laboratory.

Keywords: Anopheles culicifacies; Malaria; Plasmodium vivax; malaria refractory

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1365-3156.2005.01556.x

Affiliations: National Institute of Malaria Research, Delhi, India

Publication date: February 1, 2006

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