Skip to main content

Free Content Histoplasmine and paracoccidiodine epidemiological study in Upata, Bolívar state, Venezuela

Download Article:

You have access to the full text article on a website external to ingentaconnect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library


Summary Objective 

To determine the prevalence of histoplasmosis and paracoccidiomycosis in Upata, a city in Bolívar state, Venezuela. Methods 

Cutaneous tests on 397 volunteers, 204 with histoplasmine and 193 with paracoccidioidine. Epidemiological data were collected in a protocol sheet. Readings were performed at 24 and 48 h post-injection, by the same observer, and a positive reaction was defined as hardened papule of 5 mm or more. Results 

Histoplasmine tests were positive in 19.6% and 34.0% at 24 and 48 h after antigens injection with a significant increase of reactivity (P = 0.0019). Paracoccidiodine tests were positive in 11.3% and 19.7% at 24 and 48 h respectively and this difference was also significant (P = 0.004). Risk factors which could explain these levels of reactivity could not be clearly identified. Cultures and animal inoculation from soil samples for fungus isolation were negative. Conclusions 

Paracoccidioidomycoses and histoplasmosis are endemic in Upata.

Keywords: Bolivar state; Venezuela; dermal reaction; histoplasmine; paracoccidioidine

Document Type: Research Article


Affiliations: 1: Departamento de Parasitología y Microbiología, Universidad de Oriente, Bolívar, Venezuela 2: Departamento de Medicina, Universidad de Oriente, Bolívar, Venezuela 3: Distrito Sanitario II Sección de Epidemiología, San Félix, Venezuela 4: Departamento de Ciencias Fisiológicas Universidad de Oriente, Bolívar, Venezuela

Publication date: March 1, 2005


Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more
Real Time Web Analytics