Plasmodium falciparum multiplicity correlates with anaemia in symptomatic malaria
In 366 Ghanaian children with symptomatic Plasmodium falciparum malaria, low haemoglobin levels and severe anaemia were associated with a high multiplicity of infection (MOI) and with distinct merozoite surface protein alleles. High MOI not only reflects premunition but may also contribute to anaemia in symptomatic malaria.
Document Type: Research Article
Affiliations: 1: Institut für Tropenmedizin, Medizinische Fakultät Charité, Humboldt Universität zu Berlin, Germany 2: Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Centre, Amsterdam, The Netherlands 3: Regional Health Administration, Ministry of Health, Takoradi, Ghana 4: School of Medicine and Health Sciences, University for Development Studies, Tamale, Ghana
Publication date: 2003-10-01