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Free Content Plasmodium falciparum multiplicity correlates with anaemia in symptomatic malaria

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In 366 Ghanaian children with symptomatic Plasmodium falciparum malaria, low haemoglobin levels and severe anaemia were associated with a high multiplicity of infection (MOI) and with distinct merozoite surface protein alleles. High MOI not only reflects premunition but may also contribute to anaemia in symptomatic malaria.

Keywords: Plasmodium falciparum; anaemia; malaria; msp

Document Type: Research Article

DOI: http://dx.doi.org/10.1046/j.1365-3156.2003.01117.x

Affiliations: 1: Institut für Tropenmedizin, Medizinische Fakultät Charité, Humboldt Universität zu Berlin, Germany 2: Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Centre, Amsterdam, The Netherlands 3: Regional Health Administration, Ministry of Health, Takoradi, Ghana 4: School of Medicine and Health Sciences, University for Development Studies, Tamale, Ghana

Publication date: October 1, 2003



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