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Free Content Myocardial damage in falciparum malaria detectable by cardiac troponin T is rare

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Summary objectives 

To estimate the prevalence of myocardial damage in falciparum malaria by serum concentration of cardiac troponin T. methods 

Retrospective study of stored sera and patient files; assessment of acute myocardial damage by serum concentration or activity of cardiac troponin T, creatine kinase, creatine kinase MB and myoglobin and by routine electrocardiography. results 

A total of 161 patients with falciparum malaria were included in the study; troponin T was elevated in one case (0.6%), no CK-MB elevations were found, myoglobin was elevated in 10 of 161 patients (6.2%), all of whom were elderly and had concomitant elevated serum concentration levels of cystatin C; ECG abnormalities were seen in 23 patients. conclusion 

Assessed by troponin T, myocardial damage in falciparum malaria is rare.

Keywords: heart; malaria; myocarditis; myoglobin; troponin T

Document Type: Research Article


Affiliations: 1: Institut für Tropenmedizin, Charité, Humboldt-Universität zu Berlin, Germany 2: Institut für Tropenmedizin, Eberhard-Karls-Universität, Tübingen, Germany 3: Medizinische Klinik mit Schwerpunkt Infektiologie, Charité Campus Virchow, Humbold-Universität zu Berlin, Germany 4: Abteilung für Laboratoriumsmedizin am Unfallkrankenhaus Berlin, Germany

Publication date: January 1, 2003

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