Skip to main content

Toxic activities of the plant Jatropha curcas against intermediate snail hosts and larvae of schistosomes

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Summary

The aim of studies on plant molluscicides is to complement methods for controlling snails acting as intermediate hosts of schistosomes. We report on the toxic activity of extracts from Jatropha curcas L. (Euphorbiaceae) against snails transmitting Schistosoma mansoni and S. haematobium. We studied different extracts' effects on infectious larvae, cercariae and miracidia of S. mansoni. Compared to aqueous extract, methanol extract showed the highest toxicity against all tested organisms with LC100-values of 25 p.p.m. for cercariae and the snail Biomphalaria glabrata and 1 p.p.m. for the snails Bulinus truncatus and B. natalensis. Attenuation of cercariae leading to reduced infectivity in mice could be achieved in concentrations below those exerting acute toxicity. In view of our results and the ongoing exploitation of J. curcas for other purposes, this plant could become an affordable and effective component of an integrated approach to schistosomiasis control.

Keywords: Biomphalaria; Bulinus; Jatropha curcas; Schistosoma; attenuation; cercariae; miracidia; molluscicide; nontarget organisms; toxicity

Document Type: Research Article

DOI: https://doi.org/10.1046/j.1365-3156.2000.00573.x

Affiliations: Department of Tropical Hygiene and Public Health, University of Heidelberg, Germany

Publication date: 2000-06-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more