Glucose-6-phosphate dehydrogenase deficiency in northern Vietnam
Glucose-6-phosphate dehydrogenase (G6PD) deficiency was evaluated in 1676 schoolboys in northern Vietnam. The trait was nearly absent in boys of the Kinh (0.5%) and the Mong (0.7%) ethnic groups that traditionally have lived outside malaria transmission areas. Prevalences among ethnic groups living in the foothills, the breeding area of the main malaria vector Anopheles minimus, ranged from 9.7% to 31%. These findings support the hypothesis of a selective advantage of the trait in Plasmodium falciparum-endemic areas.
Document Type: Research Article
Affiliations: 1: Belgian Administration for Development Cooperation, Brussels, Belgium 2: National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam 3: Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
Publication date: March 1, 2000