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Aggressive Kaposi's sarcoma in a 6-month-old African infant: case report and review of the literature

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Abstract:

Summary

Kaposi's sarcoma (KS), known to exist in Africa for a century now, was rare in children and unknown in the newborn. With the onset of the HIV/AIDS epidemic, a more aggressive, disseminated type of KS (AKS) was recognized. Recently KS was diagnosed in a 6-month-old infant in Tanzania. Data support the notion that HHSV8 infectivity can be potentiated with HIV infection and thus produce multiple lesions in different anatomical sites early in life. Furthermore, the available evidence would suggest a nonsexual route of HHSV8 infection, possibly from mother to fetus.

Keywords: African; Kaposi's sarcoma; infant; transmission route

Document Type: Research Article

DOI: http://dx.doi.org/10.1046/j.1365-3156.2000.00523.x

Affiliations: 1: Department of Paediatrics and Child Health, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania 2: Department of Surgery, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania

Publication date: February 1, 2000

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