Skip to main content

The impact of population level deworming on the haemoglobin levels of schoolchildren in Tanga, Tanzania

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Summary

The impact of albendazole (400 mg) and praziquantel (40 mg/kg body weight) treatment of schoolchildren was compared with placebo according to the presence of anaemia (haemoglobin concentration < 11.0 g/dl) and heavy (> 5000 epg) or light (< 5000 epg) hookworm egg load. The study was conducted in rural Tanga. Medication was administered in September 1994 and children were followed-up in January 1995. Overall, anthelminthic treatment reduced the fall in haemoglobin concentration compared with that observed in the placebo group (− 0.11 g/dl vs. − 0.35 g/dl; = 0.02). Anthelminthic treatment was of greatest benefit to the 9% of children with both anaemia and heavy hookworm egg load (+ 0.67 g/dl vs. − 0.67 g/dl) and was also of significant benefit to the 38% of children with anaemia and light hookworm egg load (+ 0.07 g/dl vs. − 0.21 g/dl). It was of no significant benefit to children who were not anaemic. This study suggests that single-dose anthelminthic treatment distributed in schools in this area achieves haematological benefits in nearly half of children infected with S. haematobium and geohelminths (37% of total population).

Keywords: Ascaris lumbricoides; Schistosoma haematobium; Tanzania; Trichuris trichiura; anaemia; deworming; gut helminths; hookworm; schoolchildren

Document Type: Research Article

DOI: http://dx.doi.org/10.1046/j.1365-3156.1999.00486.x

Affiliations: 1: Wellcome Trust Centre for the Epidemiology of Infectious Diseases, University of Oxford 2: Centre for International Child Health, Institute of Child Health, University College, London 3: UKUMTA (Tanzania Partnership for Child Development), Dar es Salaam, Tanzania 4: Tanzania Food and Nutrition Centre, Dar es Salaam, Tanzania

Publication date: November 1, 1999

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Partial Open Access Content
Partial Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more