Short communication: Dengue serotype 2 subtype III (‘Jamaica’) epidemic in Santa Cruz, Bolivia
Abstract:Summarybackground During the past decade, dengue and dengue haemorrhagic fever (DHF) have become a public health problem in various Latin American countries. Indications of increased dengue cases in the city of Santa Cruz, Bolivia, early in 1997 were promptly investigated.
methods We conducted a sample sero-survey in one district of the city. Levels of antidengue IgM were determined and genetic analysis was performed on virus isolates.
results IgM antibodies were detected in 6.5% (95% CI: 3.4%– 9.6%) of adults (over 15 years old) and 5.1% (2.0%– 8.2%) of children (5–7 years old). Dengue virus serotype 2 subtype III (‘Jamaica’) was isolated.
conclusions The estimated attack rates are compatible with a dengue epidemic in Santa Cruz. Isolation of dengue-2 ‘Jamaica’ virus documents the further spread of this subtype from the Caribbean via Brazil into South America. Increased DHF preparedness seems mandatory.
Document Type: Original Article
Affiliations: 1: Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium 2: Centro Nacional de Enfermedades Tropicales, Santa Cruz, Bolivia 3: Centers for Disease Control, San Juan, Puerto Rico
Publication date: November 1, 1998