Skip to main content

Relative versus absolute risk of dying reduction after using insecticide-treated nets for malaria control in Africa

Buy Article:

$43.00 plus tax (Refund Policy)

Four recently completed large-scale randomized controlled trials have assessed the impact of insecticide-treated bednets and curtains on overall child mortality in Africa. These results have sparked numerous discussions among implementing agency representatives and researchers about the public health significance of the results. For the interpretation of impact, most of the arguments have been based on the observed decrease in protective efficacy (a relative measure of impact) with increasing malaria transmission (range: 14–29%, regression for trend: F = 245 on 1,2 DF, P < 0.003). However, an analysis of the absolute measure of impact (the risk difference) showed a different pattern. The impact ranges from 3.8 to 6.9 lives saved per 1000 children protected per year, without a significant trend (F = 2.8 on 1,2 DF, P = 0.2) and with equally high values in both low and high transmission sites. When assessing the public health importance of an intervention, both relative and absolute decrease in risk should be considered.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Keywords: Africa; Malaria; insecticide-treated bednets (mosquito nets); malaria prevention and control; mortality

Document Type: Research Article

Affiliations: 1: Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland , 2: Ifakara Centre, Ifakara, Tanzania , 3: Prince Leopold Institute of Tropical Medicine, Antwerpen, Belgium , 4: Navrongo Health Research Centre, Navrongo, Ghana , 5: UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), Geneva, Switzerland

Publication date: 01 April 1998

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more