Indirect haemagglutination test using monoclonal antibody-affinity purified antigens for diagnosis of human paragonimiasis due to Paragonimus heterotremus
Abstract:An indirect haemagglutination test (IHA) using antigens purified by monoclonal antibody-affinity chromatography was developed for the diagnosis of human paragonimiasis caused by Paragonimus heterotremus. Sera from patients with paragonimiasis (n= 30) were evaluated, along with sera from other parasitic infections (n= 92), pulmonary tuberculosis (n= 18) and healthy controls (n = 30). The sensitivity, specificity as well as positive and negative predictive value of the IHA, calculated at the prevalence of disease at 17.6%, were all 100%.
Document Type: Research Article
Affiliations: 1: Department of Parasitology, Faculty of Medicine, Khon Kaen University, Thailand, 2: Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Thailand, 3: Institute of Medicine, Suranaree University of Technology, Nakhonratchasima, Thailand, 4: Department of Parasitology, Faculty of Medicine, Chiang Mai University, Thailand, 5: Department of Microbiology and Immunology, Faculty of Tropical Medicine, Bangkok, Thailand
Publication date: January 1, 1998