Skip to main content

Seroepidemiology of abdominal angiostrongyliasis: the standardization of an immunoenzymatic assay and prevalence of antibodies in two localities in Southern Brazil

Buy Article:

$51.00 plus tax (Refund Policy)

Abdominal angiostrongyliasis is a nematode disease produced by Angiostrongylus costaricensis, a metastrongylid parasite of wild rodents. Accidental human infection occurs through ingestion of food or water contaminated with third‐stage larvae present in the mucous secretion of terrestrial molluscs. An ELISA test was standardized for detection of IgG antibodies recognizing a surface antigen prepared from female worms. Competitive absorption of sera with Ascaris suum crude antigen resulted in a test with 86% sensitivity and 83% specificity. The disease is endemic in Southern Brazil and a number of cases are diagnosed every year through anatomo‐pathological examination of biopsies or surgical specimens, since no other diagnostic method is available. According to seroepidemiological studies, prevalences in two transmission foci are 29.8 and 66%, attesting to the widespread occurrence of the infection in those endemic areas.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: Brazil; ELISA; angiostrongyliasis

Document Type: Original Article

Affiliations: 1: Department of Immunology, WHO Collaborating Center for Research and Training in the Immunology of Parasitic Diseases, Instituto Oswaldo Cruz, Rio de Janeiro and Instituto Biociencias, PUCRS, Porto Alegre, Brazil, 2: Universidade de Passo Fundo-RS, Brazil

Publication date: 1997-03-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more