Extrinsic allergic alveolitis

Authors: ISMAIL, Tengku; MCSHARRY, Charles¹; BOYD, Gavin¹

Source: Respirology, Volume 11, Number 3, May 2006 , pp. 262-268(7)

Publisher: Blackwell Publishing

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Abstract:

Extrinsic allergic alveolitis

ISMAIL T, Mcsharry C, BOYD G. Respirology 2006; 11: 262–268 Abstract:

Extrinsic allergic alveolitis (also known as hypersensitivity pneumonitis) is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response in the distal bronchioles and alveoli and subjects may present clinically with a variety of symptoms. The aims of this review are to describe the current concepts of the immunological response, the diverse clinical presentation of this disease, the relevant investigations and management, and areas for future studies.

Keywords: cytokines; extrinsic allergic alveolitis; hypersensitivity pneumonitis; immunopathogenesis

Document Type: Review article

DOI: 10.1111/j.1440-1843.2006.00839.x

Affiliations: 1: North Glasgow University Hospitals NHS Trust, Glasgow, UK

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