Tardive dyskinesia with ziprasidone and citalopram use in an elderly female patient

Authors: OZBULUT, Omer; EMUL, Murat; GULER, Ozkan; GECICI, Omer

Source: Psychogeriatrics, Volume 8, Number 2, June 2008 , pp. 96-97(2)

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Abstract:

Tardive dyskinesia (TD) is occasionally an irreversible condition caused by antipsychotic treatment. Second-generation antipsychotics are considered to have less extrapyramidal effects, including causing TD. Herein, we present a case of TD following ziprasidone use. A 67 year-old woman started to hear voices and `see' people speaking to her, especially while praying. She presented to our clinic with anxiety, anhedonia, dysphoria, and auditory hallucinations. She was admitted with a diagnosis of depressive disorder with psychotic features. Citalopram 20 mg/day and ziprasidone 40 mg b.i.d. were started. After her symptoms had been relieved, the patient was was discharged and with monthly follow up. At her first visit 1 month after discharge, orofacial dyskinesia was found on physical examination. Ziprasidone may be associated with TD, even in someone who has never been exposed to a traditional neuroleptic. However, concomittant treatment with a serotonin reuptake inhibitor in the present case may have favored the appearance of TD.

Keywords: citalopram; tardive dyskinesia; ziprasidone

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1479-8301.2008.00226.x

Publication date: 2008-06-01