Do we still need a malaria vaccine?

Authors: GREENWOOD, B.; TARGETT, G.

Source: Parasite Immunology, Volume 31, Number 9, September 2009 , pp. 582-586(5)

Buy & download fulltext article:

You have access to the full text article on a website external to ingentaconnect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library

Abstract:

Summary

An unexpectedly large reduction in the burden of malaria has recently been achieved in a number of malaria endemic countries following the scaling up of effective treatment and simple vector control programmes. These achievements question the need for a partially effective malaria vaccine targeted at disease prevention. If an anti-disease vaccine is to replace or supplement existing control measures a high level of efficacy, sustained over a number of years, will be required. Recent successes in malaria control have re-awakened interest in the possibility of malaria elimination in areas where this was not previously considered to be a feasible objective. Malaria vaccines with transmission-blocking properties could play a key role in future elimination programmes.

Keywords: elimination; malaria; vaccine

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1365-3024.2009.01140.x

Publication date: 2009-09-01