Acral Peeling Skin Syndrome: A Case of Two Brothers

Authors: Wakade, Oojwala¹; Adams, Beth²; Shwayder, Tor²

Source: Pediatric Dermatology, Volume 26, Number 3, May/June 2009 , pp. 328-330(3)

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Abstract:

We report two brothers of Middle Eastern descent with consanguineous parents who present with numerous fragile, flaccid blisters on the hands and feet. In addition to spontaneous peeling, they can manually peel skin from acral areas without pain. The symptoms worsen with warm temperatures, excessive water exposure, and perspiration. Two biopsies from flaccid blisters on the feet were taken from the older brother, which revealed cleavage at the level of the stratum corneum. A diagnosis of acral peeling skin syndrome was made.

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1525-1470.2009.00917.x

Affiliations: 1: Wayne State University, School of Medicine, Detroit, Michigan 2: Department of Dermatology, Henry Ford Hospital, Detroit, Michigan

Publication date: 2009-05-01