Congenital Disseminated Pyogenic Granuloma

Authors: Browning, John C.¹; Eldin, Karen W.²; Kozakewich, Harry P. W.³; Mulliken, John B.⁴; Bree, Alanna F.¹

Source: Pediatric Dermatology, Volume 26, Number 3, May/June 2009 , pp. 323-327(5)

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Abstract:

In the past pyogenic granuloma (PG) in infancy has been easily confused clinically and histopathologically with infantile hemangioma (IH). In 2000 North and colleagues discovered that IH is immunopositive for GLUT-1, a glucose transporter which is also expressed in placental capillaries ( 1). GLUT-1 staining is negative in pyogenic granuloma. We report two newborns with congenital disseminated PG who were otherwise healthy. In both of these cases, negative GLUT-1 staining supported the proper diagnosis.

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1525-1470.2008.00858.x

Affiliations: 1: Departments of Dermatology 2: Pathology, and 3: Plastic Surgery, Baylor College of Medicine, Houston, Texas 4: Harvard University School of Medicine, Boston, Massachusetts

Publication date: 2009-05-01