The Hair Collar Sign as a Marker for Neural Tube Defects

Author: Harrington, Brian C.

Source: Pediatric Dermatology, Volume 24, Number 2, March/April 2007 , pp. 138-140(3)

Publisher: Blackwell Publishing

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Abstract:

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The hair collar sign has been described as a marker of cranial dysraphism, including encephaloceles, meningoceles, and heterotropic brain tissue. This report describes a male born with a hair collar sign who subsequently was found to have a Klippel-Feil anomaly, diastematomyelia, multiple segmental spine and rib anomalies, and a translocation between chromosomes 1 and 4; t(1;4) (q44;q10). While not previously documented, spine abnormalities may be an associated abnormality with the hair collar sign. Physicians should consider radiographic evaluation of the spine in all newborns with a hair collar sign, as well as genetic screening.

Document Type: Research article

DOI: 10.1111/j.1525-1470.2007.00360.x

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