Clinical characteristics of upper airway resistance syndrome

Authors: Watanabe, Takuya¹; Mikami, Akira¹; Taniguchi, Mitsutaka²; Motonishi, Masamichi³; Honda, Hideharu³; Kyotani, Kyoko³; Uruha, Shigehiko³; Terashima, Kiyoji³; Teshima, Yoshio³; Egawa, Isao²; Sugita, Yoshiro¹; Takeda, Masatoshi³

Source: Psychiatry and Clinical Neurosciences, Volume 53, Number 2, April 1999 , pp. 331-333(3)

Publisher: Wiley-Blackwell

Buy & download fulltext article:

Price: $48.00 plus tax (Refund Policy)

Abstract:

Polysomnographic findings and clinical symptoms were investigated in 14 cases of upper airway resistance syndrome. The mean scores of the Epworth sleepiness scale and self-rating depression scale in eight cases were 13.5 and 38.6, respectively. The mean sleep latency of the multiple sleep latency test in four cases was 10.2 min. Seven cases were treated with continuous positive airway pressure (CPAP), and one with hormone replacement therapy. The most common symptom was daytime sleepiness. Five cases had hypertension. CPAP reduced increasing negative esophageal pressure (Pes) and frequency of EEG arousals, and improved hypertension in one case. Hormone replacement therapy ameliorated increasing negative Pes and clinical symptoms.

Keywords: continuous positive airway pressure; daytime sleepiness; electroencephalogram arousal; hormone replacement therapy; snoring; upper airway resistance syndrome

Document Type: Research article

DOI: http://dx.doi.org/10.1046/j.1440-1819.1999.00554.x

Affiliations: 1: Department of Medical Science III, School of Health and Sport Sciences, Osaka University, 2: Osaka Kaisei hospital, and, 3: Department of Neuropsychiatry, Osaka University Medical School, Osaka, Japan

Publication date: 1999-04-01