Annals of the New York Academy of Sciences

Preface
pp. xii-xii(1)

The Sense of Smell: Reception of Flavors
pp. 1-6(6)
Author: Breer, H.

Receptor for Advanced Glycation End Products
pp. 7-13(7)
Authors: Ramasamy, Ravichandran; Yan, Shi Fang; Herold, Kevan; Clynes, Raphael; Schmidt, Ann Marie

Central Nervous System Regulation of Energy Metabolism
pp. 14-19(6)
Authors: Nogueiras, Ruben; Tschöp, Matthias H.; Zigman, Jeffrey M.

Determination of N^ɛ -(Carboxymethyl)lysine in Foods and Related Systems
pp. 20-24(5)
Author: Ames, Jennifer M.

Food Anoxia and the Formation of Either Flavor or Toxic Compounds by Amino Acid Degradation Initiated by Oxidized Lipids
pp. 25-29(5)
Authors: Hidalgo, Francisco J.; Zamora, Rosario

Post-Schiff Base Chemistry of the Maillard Reaction: Mechanism of Imine Isomerization
pp. 30-37(8)
Authors: Chu, Fong Lam; Yaylayan, Varoujan A.

Usefulness of Antibodies for Evaluating the Biological Significance of AGEs
pp. 38-41(4)
Authors: Nagai, Ryoji; Fujiwara, Yukio; Mera, Katsumi; Motomura, Keita; Iwao, Yasunori; Tsurushima, Keiichiro; Nagai, Mime; Takeo, Kazuhiro; Yoshitomi, Makiko; Otagiri, Masaki; Ikeda, Tsuyoshi

Receptor for Advanced Glycation End Product Expression in Experimental Diabetic Retinopathy
pp. 42-45(4)
Authors: Wang, Yumei; vom Hagen, Franziska; Pfister, Frederick; Bierhaus, Angelika; Feng, Yuxi; Gans, Reinhold; Hammes, Hans-Peter

Advanced Glycation End Product Homeostasis: Exogenous Oxidants and Innate Defenses
pp. 46-52(7)
Authors: Vlassara, Helen; Uribarri, Jaime; Cai, Weijing; Striker, Gary

Formation Mechanisms of Melanoidins and Fluorescent Pyridinium Compounds as Advanced Glycation End Products
pp. 53-58(6)
Authors: Hayase, Fumitaka; Usui, Teruyuki; Ono, Yoriyuki; Shirahashi, Yoshinobu; Machida, Tomomi; Ito, Takashi; Nishitani, Nozomu; Shimohira, Kazuhito; Watanabe, Hirohito

Advanced Glycation as a Basis for Understanding Retinal Aging and Noninvasive Risk Prediction
pp. 59-65(7)
Authors: Pawlak, Anna M.; Glenn, Josephine V.; Beattie, James R.; McGarvey, John J.; Stitt, Alan W.

The Aroma Side of the Maillard Reaction
pp. 66-71(6)
Author: Cerny, Christoph

Methylglyoxal: Its Presence in Beverages and Potential Scavengers
pp. 72-75(4)
Authors: Tan, Di; Wang, Yu; Lo, Chih-Yu; Sang, Shengmin; Ho, Chi-Tang

The RAGE Pathway: Activation and Perpetuation in the Pathogenesis of Diabetic Neuropathy
pp. 76-80(5)
Authors: Lukic, Ivan K.; Humpert, Per M.; Nawroth, Peter P.; Bierhaus, Angelika

The Role of the Amadori Product in the Complications of Diabetes
pp. 81-88(8)
Authors: Monnier, Vincent M.; Sell, David R.; Dai, Zhenyu; Nemet, Ina; Collard, Francois; Zhang, Jianye

Mitigation Strategies to Reduce Acrylamide Formation in Fried Potato Products
pp. 89-100(12)
Authors: Morales, Francisco; Capuano, Edoardo; Fogliano, Vincenzo

Therapeutic Interruption of Advanced Glycation in Diabetic Nephropathy: Do All Roads Lead to Rome?
pp. 101-106(6)
Authors: Sourris, Karly C.; Forbes, Josephine M.; Cooper, Mark E.

The Other Side of the Maillard Reaction
pp. 107-112(6)
Authors: Nagaraj, Ram H.; Biswas, Ashis; Miller, Antonia; Oya-Ito, Tomoko; Bhat, Manjunatha

Dicarbonyls Stimulate Cellular Protection Systems in Primary Rat Hepatocytes and Show Anti-inflammatory Properties
pp. 113-117(5)
Authors: Buetler, Timo M.; Latado, Hélia; Baumeyer, Alexandra; Delatour, Thierry

N-terminal Glycation of Proteins and Peptides in Foods and in Vivo
pp. 118-123(6)
Authors: Penndorf, Ilka; Li, Changhao; Schwarzenbolz, Uwe; Henle, Thomas

The Dicarbonyl Proteome: Proteins Susceptible to Dicarbonyl Glycation at Functional Sites in Health, Aging, and Disease
pp. 124-127(4)
Authors: Rabbani, Naila; Thornalley, Paul J.

Peroxyl Radicals Are Essential Reagents in the Oxidation Steps of the Maillard Reaction Leading to Generation of Advanced Glycation End Products
pp. 128-133(6)
Author: Spiteller, Gerhard

Application of Mass Spectrometry for the Detection of Glycation and Oxidation Products in Milk Proteins
pp. 134-140(7)
Authors: Meltretter, Jasmin; Pischetsrieder, Monika

Inhibition of Advanced Glycation End Products: An Implicit Goal in Clinical Medicine for the Treatment of Diabetic Nephropathy?
pp. 141-146(6)
Authors: Miyata, Toshio; Izuhara, Yuko

Inflammation and the Redox-sensitive AGE-RAGE Pathway as a Therapeutic Target in Alzheimer's Disease
pp. 147-151(5)
Authors: Maczurek, Annette; Shanmugam, Kirubakaran; Münch, Gerald

Some Natural Compounds Enhance N^ɛ-(Carboxymethyl)lysine Formation
pp. 152-154(3)
Authors: Fujiwara, Yukio; Kiyota, Naoko; Motomura, Keita; Mera, Katsumi; Takeya, Motohiro; Ikeda, Tsuyoshi; Nagai, Ryoji

Immunological Detection of N^ω-(Carboxymethyl)arginine by a Specific Antibody
pp. 155-157(3)
Authors: Mera, Katsumi; Fujiwara, Yukio; Otagiri, Masaki; Sakata, Noriyuki; Nagai, Ryoji

Isolation and Partial Characterization of Four Fluorophores Formed by Nonenzymatic Browning of Methylglyoxal and Glutamine-derived Ammonia
pp. 158-161(4)
Authors: Niquet, Celine; Pilard, Serge; Mathiron, David; Tessier, Frederic J.

Receptor for Advanced Glycation End Product Polymorphisms and Type 2 Diabetes: The CODAM Study
pp. 162-165(4)
Authors: Gaens, Katrien H.J.; van der Kallen, Carla J.H.; van Greevenbroek, Marleen M.J.; Feskens, Edith J.; Stehouwer, Coen D.A.; Schalkwijk, Casper G.

Pentosidine Effects on Human Osteoblasts in Vitro
pp. 166-172(7)
Authors: Sanguineti, Roberta; Storace, Daniela; Monacelli, Fiammetta; Federici, Alberto; Odetti, Patrizio

Strategy for the Study of the Health Impact of Dietary Maillard Products in Clinical Studies: The Example of the ICARE Clinical Study on Healthy Adults
pp. 173-176(4)
Authors: Pouillart, Philippe; Mauprivez, Hélène; Ait-Ameur, Lamia; Cayzeele, Amélie; Lecerf, Jean-Michel; Tessier, Frédéric J.; Birlouez-Aragon, I.

Plasma Concentration and Urinary Excretion of N^ɛ-(Carboxymethyl)lysine in Breast Milk- and Formula-fed Infants
pp. 177-180(4)
Authors: Šebeková, Katarína; Saavedra, Giselle; Zumpe, Cornelia; Somoza, Veronika; Klenovicsová, Kristína; Birlouez-Aragon, Ines

Maillard Reaction Products in the Escherichia coli-derived Therapeutic Protein Interferon Alfacon-1
pp. 181-184(4)
Authors: Mironova, Roumyana; Sredovska, Angelina; Ivanov, Ivan; Niwa, Toshimitsu

Acrolein Induces Inflammatory Response Underlying Endothelial Dysfunction: A Risk Factor for Atherosclerosis
pp. 185-189(5)
Authors: Park, Yong Seek; Taniguchi, Naoyuki

Oxidative Stress and Advanced Glycation in Diabetic Nephropathy
pp. 190-193(4)
Authors: Coughlan, Melinda T.; Mibus, Amy L.; Forbes, Josephine M.

Vitamin C-mediated Maillard Reaction in the Lens Probed in a Transgenic-mouse Model
pp. 194-200(7)
Authors: Fan, Xingjun; Monnier, Vincent M.

N^ɛ-(Carboxymethyl)lysine during the Early Development of Hypertension
pp. 201-204(4)
Authors: Baumann, Marcus; Stehouwer, Coen; Scheijen, Jean; Heemann, Uwe; Struijker Boudier, Harry; Schalkwijk, Casper

Aging, Diabetes, and Renal Failure Catalyze the Oxidation of Lysyl Residues to 2-Aminoadipic Acid in Human Skin Collagen: Evidence for Metal-catalyzed Oxidation Mediated by α-Dicarbonyls
pp. 205-209(5)
Authors: Sell, David R.; Strauch, Christopher M.; Shen, Wei; Monnier, Vincent M.

α-Dicarbonyl Compounds—Key Intermediates for the Formation of Carbohydrate-based Melanoidins
pp. 210-215(6)
Authors: Kroh, Lothar W.; Fiedler, Thorsten; Wagner, Janine

Approaches to Wine Aroma: C₁ Transfer during the Reaction between Diacetyl and Cysteine
pp. 216-219(4)
Authors: Almy, John; de Revel, Gilles

Antioxidant Activity and Chemical Properties of Crude and Fractionated Maillard Reaction Products Derived from Four Sugar-Amino Acid Maillard Reaction Model Systems
pp. 220-224(5)
Authors: Chen, Xiu-Min; Kitts, David D.

Advanced Glycation Endproducts in Chronic Heart Failure
pp. 225-230(6)
Authors: Smit, Andries J.; Hartog, Jasper W. L.; Voors, Adriaan A.; van Veldhuisen, Dirk J.

Methylglyoxal and Methylglyoxal-arginine Adducts Do Not Directly Inhibit Endothelial Nitric Oxide Synthase
pp. 231-234(4)
Authors: Brouwers, Olaf; Teerlink, Tom; van Bezu, Jan; Barto, Rob; Stehouwer, Coen D.A.; Schalkwijk, Casper G.

Kinetic Study of the Reaction of Glycolaldehyde with Two Glycation Target Models
pp. 235-240(6)
Authors: Adrover, Miquel; Vilanova, Bartolomé; Muñoz, Francisco; Donoso, Josefa

Origin and Yields of Acetic Acid in Pentose-based Maillard Reaction Systems
pp. 241-243(3)
Authors: Davidek, Tomas; Gouézec, Elisabeth; Devaud, Stéphanie; Blank, Imre

The Peptide-catalyzed Maillard Reaction: Characterization of ¹³C Reductones
pp. 244-247(4)
Authors: Garbe, Leif Alexander; Würtz, Alexander; Piechotta, Christian T.; Tressl, Roland

Model Studies on Protein Glycation: Influence of Cysteine on the Reactivity of Arginine and Lysine Residues toward Glyoxal
pp. 248-252(5)
Authors: Schwarzenbolz, Uwe; Mende, Susann; Henle, Thomas

Analysis of Amadori Peptides Enriched by Boronic Acid Affinity Chromatography
pp. 253-256(4)
Authors: Frolov, Andrej; Hoffmann, Ralf

Induction of Heat Shock Proteins and the Proteasome System by Casein-N^ɛ-(Carboxymethyl)lysine and N^ɛ-(Carboxymethyl)lysine in Caco-2 Cells
pp. 257-261(5)
Authors: Schmid, Karoline; Haslbeck, Martin; Buchner, Johannes; Somoza, Veronika

Reversal of Hyperglycemia-Induced Angiogenesis Deficit of Human Endothelial Cells by Overexpression of Glyoxalase 1 In Vitro
pp. 262-264(3)
Authors: Ahmed, Usman; Dobler, Darin; Larkin, Sarah J.; Rabbani, Naila; Thornalley, Paul J.

Pathophysiological Role of the Glyoxalase System in Renal Hypoxic Injury
pp. 265-267(3)
Authors: Kumagai, Takanori; Nangaku, Masaomi; Inagi, Reiko

A419C (E111A) Polymorphism of the Glyoxalase I Gene and Vascular Complications in Chronic Hemodialysis Patients
pp. 268-271(4)
Authors: Kalousová, Marta; Germanová, Alexandra; Jáchymová, Marie; Mestek, Oto; Tesavˇ, Vladimír; Zima, Tomáš

Succination of Proteins by Fumarate: Mechanism of Inactivation of Glyceraldehyde-3-Phosphate Dehydrogenase in Diabetes
pp. 272-275(4)
Authors: Blatnik, Matthew; Thorpe, Suzanne R.; Baynes, John W.

Dietary Advanced Glycation Endproducts and Oxidative Stress: In VivoEffects on Endothelial Function and Adipokines
pp. 276-279(4)
Authors: Stirban, Alin; Negrean, Monica; Götting, Christian; Uribarri, Jaime; Gawlowski, Thomas; Stratmann, Bernd; Kleesiek, Knut; Koschinsky, Theodor; Vlassara, Helen; Tschoepe, Diethelm

Preparation of Nucleotide Advanced Glycation Endproducts—Imidazopurinone Adducts Formed by Glycation of Deoxyguanosine with Glyoxal and Methylglyoxal
pp. 280-282(3)
Authors: Fleming, Thomas; Rabbani, Naila; Thornalley, Paul J.

Maillard Products as Biomarkers in Cancer
pp. 283-287(5)
Authors: Bachmeier, Beatrice E.; Nerlich, Andreas G.; Rohrbach, Helmut; Schleicher, Erwin D.; Friess, Ulrich

Glycation of Plasma Lipoprotein Lipid Membrane and Screening for Lipid Glycation Inhibitor
pp. 288-290(3)
Authors: Nakagawa, Kiyotaka; Ibusuki, Daigo; Yamashita, Shinji; Miyazawa, Teruo

Analysis of Amadori-glycated Phosphatidylethanolamine in the Plasma of Healthy Subjects and Diabetic Patients by Liquid Chromatography-Tandem Mass Spectrometry
pp. 291-294(4)
Authors: Miyazawa, Teruo; Ibusuki, Daigo; Yamashita, Shinji; Nakagawa, Kiyotaka

Nonenzymatically Glycated Lipoprotein ApoA-I in Plasma of Diabetic and Nephropathic Patients
pp. 295-299(5)
Authors: Lapolla, Annunziata; Brioschi, Maura; Banfi, Cristina; Tremoli, Elena; Cosma, Chiara; Bonfante, Luciana; Cristoni, Simone; Seraglia, Roberta; Traldi, Pietro

Evaluating the Extent of Protein Damage in Dairy Products: Simultaneous Determination of Early and Advanced Glycation-induced Lysine Modifications
pp. 300-306(7)
Authors: Hegele, Jörg; Parisod, Véronique; Richoz, Janique; Förster, Anke; Maurer, Sarah; Krause, René; Henle, Thomas; Bütler, Timo; Delatour, Thierry

A Novel Yellow Pigment, Furpipate, Derived from Lysine and Furfural
pp. 307-309(3)
Authors: Murata, Masatsune; Totsuka, Hana; Ono, Hiroshi

Time-dependent Component-specific Regulation of Gastric Acid Secretion-related Proteins by Roasted Coffee Constituents
pp. 310-314(5)
Authors: Rubach, M.; Lang, R.; Hofmann, T.; Somoza, V.

Maillard Reaction versus Other Nonenzymatic Modifications in Neurodegenerative Processes
pp. 315-319(5)
Authors: Pamplona, Reinald; Ilieva, Ekaterina; Ayala, Victoria; Bellmunt, Maria Josep; Cacabelos, Daniel; Dalfo, Esther; Ferrer, Isidre; Portero-Otin, Manuel

Suppression of Renal α-Dicarbonyl Compounds Generated following Ureteral Obstruction by Kidney-Specific α-Dicarbonyl/l-Xylulose Reductase
pp. 320-324(5)
Authors: Odani, Hiroko; Asami, Jun; Ishii, Aiko; Oide, Kayoko; Sudo, Takako; Nakamura, Atsushi; Miyata, Noriyuki; Otsuka, Noboru; Maeda, Kenji; Nakagawa, Junichi

Comparison of Pharmacokinetics between Highly and Mildly Modified AGE Proteins in Mice
pp. 325-327(3)
Authors: Nagai, Ryoji; Mera, Katsumi; Fujiwara, Yukio; Nagai, Mime; Otagiri, Masaki

Modification of Vimentin: A General Mechanism of Nonenzymatic Glycation in Human Skin
pp. 328-332(5)
Authors: Kueper, Thomas; Grune, Tilman; Muhr, Gesa-Meike; Lenz, Holger; Wittern, Klaus-Peter; Wenck, Horst; Stäb, Franz; Blatt, Thomas

Erratum for Ann. N.Y. Acad. Sci. 1072: 386-388: Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways. Wolfram W. Domschke, Martin F. Kagnoff, Torsten F. Kucharzik, Lloyd F. Mayer, and Stephan R. Targan, Eds.
pp. 333-333(1)

Erratum for Ann. N.Y. Acad. Sci. 1088: A1-A10: Neuroendocrine and Immune Crosstalk. George P. Chrousos, Gregory A. Kaltsas, and George Mastorakos, Eds.
pp. 334-334(1)

Erratum for Ann. N.Y. Acad. Sci. 1108: 505-514
pp. 335-335(1)

Errata for Ann. N.Y. Acad. Sci. 1111: 442-454: Coccidioidomycosis: Sixth International Symposium. Karl V. Clemons, Rafael Laniado-Laborin, and David A. Stevens, Eds.
pp. 336-336(1)

Index of Contributors
pp. 337-340(4)