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Antifungal activity of propolis on different species of Candida

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Propolis is a resinous material collected by bees from the buds or other parts of plants. It is known for its biological properties, having antibacterial, antifungal and healing properties. The antifungal activity of propolis was studied in sensitivity tests on 80 strains of Candida yeasts: 20 strains of Candida albicans, 20 strains of Candida tropicalis, 20 strains of Candida krusei and 15 strains of Candida guilliermondii. The yeasts showed a clear antifungal activity with the following order of sensitivity: C. albicans>C. tropicalis>C. krusei>C. guilliermondii. Patients with full dentures who used a hydroalcoholic propolis extract showed a decrease in the number of Candida. Zusammenfassung. 

Propolis ist ein harziges Material, das von Bienen aus Knospen oder anderen Pflanzenteilen gesammelt wird. Es ist durch seine biologischen Eigenschaften bekannt: antibakteriell, pilzhemmend, heilend. Die pilzhemmende Wirkung von Propolis wurde in Sensibilitätstests an 80 Candida-Stämmen untersucht: 20 Stämme von C. albicans, C. tropicalis, C. krusei und 15 von C. guilliermondii. Es zeigte sich folgende Reihe abnehmender Empfindlichkeit der Hefen für Propolis: C. albicans > C. tropicalis >C. krusei >C. guilliermondii. Zahnprothesen-Träger, die Propolis-Extrakt benutzten, zeigten eine Abnahme der Candida-Kolonisation.

Keywords: Candida; Gebissträger-Stomatitis; Propolis; antifungal activity; antimyzetische Aktivität; denture stomatitis; propolis

Document Type: Research Article


Affiliations: 1: Dental School, UNESP, São José dos Campos, SP, 2: University of Vale do Paraíba, IP & D, and

Publication date: November 1, 2001


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