Peripheral Neuroblastoma in a Newborn Piglet: Short Communication
Peripheral neuroblastoma (PNB) is a rare neoplasia derived from neuroepithelial cells. PNB typically presents as a greyish mass, composed of round cells with features of neuronal differentiation. Necropsy, performed on a 1-day-old piglet, revealed a mass craniodorsally located in the abdominal cavity. Histologically, the predominant population consisted of small round to ovoid cells with scanty cytoplasm and dark round nuclei, besides, there were larger neurone-like cells. Neurone-specific enolase and S-100 protein were immunohistochemically detected, while glial fibrillary acidic protein was negative. Histological and immunohistochemical findings substantiated the diagnosis of a grade II peripheral neuroblastoma. This seems to be the first description of a PNB in a newborn piglet.
Document Type: Short Communication
Affiliations: 1: Corresponding author: 0221 4236663/4; 0221 257980; firstname.lastname@example.org, Tel: 54, Fax: 054 2: Institute of Pathology, Veterinary School, National University of La Plata, PO Box 296 (B 1900 AVW), La Plata, Argentina;
Publication date: October 1, 2002