Peripheral Neuroblastoma in a Newborn Piglet: Short Communication

Authors: DIESSLER, M. E.1; IDIART, J. R.2; MASSONE, A. R.2; MACHUCA, M. A.2; PERFUMO, C. J.2

Source: Journal of Veterinary Medicine, Series A, Volume 49, Number 8, October 2002 , pp. 445-447(3)

Publisher: Wiley-Blackwell

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Abstract:

Summary

Peripheral neuroblastoma (PNB) is a rare neoplasia derived from neuroepithelial cells. PNB typically presents as a greyish mass, composed of round cells with features of neuronal differentiation. Necropsy, performed on a 1-day-old piglet, revealed a mass craniodorsally located in the abdominal cavity. Histologically, the predominant population consisted of small round to ovoid cells with scanty cytoplasm and dark round nuclei, besides, there were larger neurone-like cells. Neurone-specific enolase and S-100 protein were immunohistochemically detected, while glial fibrillary acidic protein was negative. Histological and immunohistochemical findings substantiated the diagnosis of a grade II peripheral neuroblastoma. This seems to be the first description of a PNB in a newborn piglet.

Document Type: Short Communication

DOI: http://dx.doi.org/10.1046/j.1439-0442.2002.00480.x

Affiliations: 1: Corresponding author: 0221 4236663/4; 0221 257980; diessler@fcv.medvet.unlp.edu.ar, Tel: 54, Fax: 054 2: Institute of Pathology, Veterinary School, National University of La Plata, PO Box 296 (B 1900 AVW), La Plata, Argentina;

Publication date: October 1, 2002

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