IngentaConnect International consensus statement on an update of the classificat...

Authors: MIYAKIS, S.¹; LOCKSHIN, M. D.²; ATSUMI, T.³; BRANCH, D. W.⁴; BREY, R. L.⁵; CERVERA, R.⁶; DERKSEN, R. H. W. M.⁷; DE GROOT, P. G.⁷; KOIKE, T.³; MERONI, P. L.⁸; REBER, G.⁹; SHOENFELD, Y.¹⁰; TINCANI, A.¹¹; VLACHOYIANNOPOULOS, P. G.¹²; KRILIS, S. A.¹

Source: Journal of Thrombosis and Haemostasis, Volume 4, Number 2, February 2006 , pp. 295-306(12)

Publisher: Blackwell Publishing

Abstract:

Summary.

New clinical, laboratory and experimental insights, since the 1999 publication of the Sapporo preliminary classification criteria for antiphospholipid syndrome (APS), had been addressed at a workshop in Sydney, Australia, before the Eleventh International Congress on antiphospholipid antibodies. In this document, we appraise the existing evidence on clinical and laboratory features of APS addressed during the forum. Based on this, we propose amendments to the Sapporo criteria. We also provide definitions on features of APS that were not included in the updated criteria.

Keywords: anticardiolipin; antiphospolipid syndrome; β2 glycoprotein-I; classification criteria; lupus anticoagulant; thrombosis

Document Type: Special article

DOI: 10.1111/j.1538-7836.2006.01753.x

Affiliations: 1: St George Hospital, University of New South Wales, Sydney, Australia 2: Hospital for Special Surgery, Cornell Medical Center, New York, NY, USA 3: Hokkaido University, Sapporo, Japan 4: University of Utah Health Sciences Center, Salt Lake City, UT 5: University of Texas Health Science Center, San Antonio, TX, USA 6: Hospital Clinic, Barcelona, Spain 7: University Medical Center, Utrecht, The Netherlands 8: Istituto Auxologico Italiano, University of Milan, Milan, Italy 9: University Hospital, Geneva, Switzerland 10: Sheba Medical Center, Tel-Hashomer and Tel Aviv University, Israel 11: Spedali Civili, University of Brescia, Italy 12: Department of Pathophysiology, University of Athens, Greece

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International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)