Skip to main content

Free Content Effect of upper airway surgery on heart rate variability in patients with obstructive sleep apnoea syndrome

Download Article:

You have access to the full text article on a website external to Ingenta Connect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library



To determine whether surgery influences cardiovascular autonomic modulation in obstructive sleep apnoea syndrome (OSAS), the present study was performed to evaluate the effect of upper airway (UA) surgery on heart rate variability (HRV) using frequency domain analysis for patient groups who have had either successful or unsuccessful surgery. We compared body mass index (BMI), polysomnographic [apnoea index (AI), apnoea‐hypopnoea index (AHI), minimum SaO2] and HRV [very low frequency (VLF) power, low frequency (LF) power, high frequency (HF) power, HF/LF ratio, LFnu = LF/(LF + HF), HFnu = HF/(LF + HF)] parameters between the unsuccessful (n =14) and successful (n =22) surgical groups before and after UA surgery. Significant changes were observed for the successful patient group with respect to mean AI (from 29.1 ± 21.3 to 2.0 ± 3.2 events h−1, P <0.001), AHI (from 38.6 ± 20.0 to 5.6 ± 5.1 events h−1, P < 0.001), minimum SaO2 (from 73.3 ± 12.7 to 86.3 ± 6.5%, P <0.001), VLF power (from 25599 ± 12906 to 20014 ± 9839 ms2, P =0.013), LF power (from 17293 ± 7278 to 14155 ± 4980 ms2, P =0.016), LFnu (from 0.700 ± 0.104 to 0.646 ± 0.128, P =0.031) and HFnu (from 0.300 ± 0.104 to 0.354 ± 0.128, P =0.031); however, mean BMI, HF power and LF/HF ratio did not change significantly after UA surgery. No significant changes were observed in the unsuccessful surgical group. Successful UA surgery may improve cardiac sympathetic and parasympathetic modulation in patients with OSAS.

Document Type: Research Article


Affiliations: 1: Department of Otorhinolaryngology–Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea 2: Departments of Otolaryngology 3: Neurology, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea

Publication date: June 1, 2012


Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more