Future Directions of Drug-Eluting Stents

Authors: KUKREJA, NEVILLE; ONUMA, YOSHINOBU; SERRUYS, PATRICK W.

Source: Journal of Interventional Cardiology, Volume 22, Supplement 1, April 2009 , pp. S96-S105(10)

Publisher: Wiley-Blackwell

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Abstract:

Coronary artery stents have changed the face of interventional cardiology since their introduction in 1986. The commercial release of drug-eluting stents in 2002 promised to abolish in-stent restenosis as the predominant clinical limitation following stent implantation. Concerns raised about increased risks of adverse events with drug-eluting stents now appear unfounded but have heralded a new era of research, where only hard clinical end-points in sufficiently large numbers of patients are considered adequate. In this review, we highlight some of the potential future directions of drug-eluting stents including specialized stent platforms (including dedicated bifurcation stents), fully degradable stents, and the potential use of stents to prevent cardiac events.

(J Interven Cardiol 2009;22:S96-S105)

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1540-8183.2009.00455.x

Affiliations: 1: Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands

Publication date: 2009-04-01

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