Toward an Implantable Wireless Cardiac Monitoring Platform Integrated with an FDA-Approved Cardiovascular Stent

Authors: CHOW, ERIC Y.; BEIER, BROOKE L.¹; FRANCINO, ANTONIO²; CHAPPELL, WILLIAM J.³; IRAZOQUI, PEDRO P.¹

Source: Journal of Interventional Cardiology, Volume 22, Number 5, October 2009 , pp. 479-487(9)

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Abstract:

Continuous monitoring of blood pressure from a minimally invasive device in the pulmonary artery can serve as a diagnostic and early warning system for cardiac health. The foremost challenge in such a device is the wireless transfer of data and power from within the blood vessel to an external device while maintaining unrestricted flow through the artery. We present a miniaturized system, which is attached to the outer surface of a regular or drug-eluting FDA-approved stent. When expanded, the stent maintains a patent vessel lumen while allowing contact between the electronic sensors and the blood supply. The stent-based antenna can be used for both wireless telemetry and power transfer for the implanted electronics. Using the stent platform as both a radiating antenna and a structural support allows us to take advantage of an FDA-approved device whose safety and surgical procedure are well established. The electronics package has been reduced to an area of less than 1 mm², with a thickness under 300 μm. A minimally invasive implantation procedure allows the delivery of the stent-based implant in nearly any major vessel of the body. This article describes an initial prototype with two stents configured as a single dipole, a 2.4-GHz transmitter microchip, and a battery, and validates transcutaneous transmission through ex vivo and in vivo porcine studies. The results demonstrate the feasibility of a stent-based wireless platform for continuous monitoring of blood pressure.

(J Interven Cardiol 2009;22:479-487)

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1540-8183.2009.00483.x

Affiliations: 1: Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 2: Institut del Torax, Hospital Clinic, Barcelona, Spain 3: School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana

Publication date: 2009-10-01

Toward an Implantable Wireless Cardiac Monitoring Platform Integrated with an FDA-Approved Cardiovascular Stent

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