Acute Left Main Occlusion During Percutaneous Coronary Intervention Associated with Heparin Induced Thrombocytopenia with Thrombosis Syndrome

Authors: ZIAKAS, ANTONIOS; GAVRILIDIS, STAVROS; MAKRIS, PANTELIS; LOURIDAS, GEORGE

Source: Journal of Interventional Cardiology, Volume 18, Number 2, April 2005 , pp. 139-144(6)

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Abstract:

A 76-year-old male was admitted with Braunwald IIIB unstable angina and treated with intravenous heparin. Coronary angiography 20 days later revealed a severe stenosis in the left circumflex artery. During coronary angioplasty thrombus developed in the circumflex artery, extended in the left main and lead to its occlusion. Normal left coronary artery patency and flow were achieved after intracoronary and intravenous administration of abciximab, and multiple stenting. Platelet-count decrease and an ELISA assay documented the presence of heparin-induced thrombocytopenia with thrombosis syndrome (HITTS). HITTS should be suspected after acute thrombus formation during coronary angioplasty.

(J Interven Cardiol 2005;18:139–144)

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1540-8183.2005.04070.x

Affiliations: 1: 1st Department of Cardiology, AHEPA University Hospital, Thessaloniki, Greece

Publication date: 2005-04-01