Incidental Findings in CT Colonography: Literature Review and Survey of Current Research Practice

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Incidental fndings (IFs) of potential medical signifcance are seen in approximately 5-8 percent of asymptomatic subjects and 16 percent of symptomatic subjects participating in large computed tomography (CT) colonography (CTC) studies, with the incidence varying further by CT acquisition technique. While most CTC research programs have a well-defned plan to detect and disclose IFs, such plans are largely communicated only verbally. Written consent documents should also inform subjects of how IFs of potential medical signifcance will be detected and reported in CTC research studies.

Document Type: Research Article


Affiliations: 1: Postdoctoral Research Fellow at the Mayo Clinic Department of Radiology. 2: The former Associate Chair of Radiology Research at the Mayo Clinic Department of Radiology and Medical Director of the CT Clinical Innovation Center. He is also a consultant in gastrointestinal imaging at the Mayo Clinic. 3: Adjunct Professor of Radiology at the Mallinckrodt Institute of Radiology at Washington University and Medical Director at the Center for Diagnostic Imaging in Chesterfield, MO. 4: Radiology resident at the Mayo Clinic Department of Radiology. 5: Currently a third-year medical student attending the Mayo Clinic School of Medicine. 6: Medical anthropologist and the Associate Director of Mayo's Program in Professionalism and Bioethics. 7: The Program Manager for Bioethics Research at the Mayo Clinic. 8: The McKnight Presidential Professor of Law, Medicine & Public Policy; Faegre & Benson Professor of Law; and a Faculty Member in the Center for Bioethics at the University of Minnesota.

Publication date: June 1, 2008

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